Endacea, Inc., an emerging biopharmaceutical company, is developing a series of proprietary A1 adenosine receptor (AR) antagonists as drug candidates for a number of medical indications, including:  1) inflammation, including sepsis and asthma; and 2) renal impairment.  Endacea is advancing the company’s lead compound A1 AR antagonist, L-97-1, as an i.v. anti-sepsis drug candidate and as a post-exposure medical countermeasure for plague and other biodefense indications.  Endacea is also developing a sensitive and specific biomarker for sepsis as a companion diagnostic for Endacea’s i.v. anti-sepsis drug candidate and for other uses.


First Flight Venture Center
2 Davis Drive
RTP, NC 27709

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University Affiliation:
University of Pennsylvania

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(919) 406-1888
(919) 406-1838
Mailing Address:
PO Box 12076
RTP, NC 27709